The Liang Lab @ U of Minnesota

Our mission is to develop innovative gene-editing technologies for precise and durable therapeutic applications. By combining expertise in genome engineering, molecular biology, and immunotherapy, we strive to advance cutting-edge solutions for targeting genetic diseases.

Shun-Qing (Simon) Liang, PhD

Principal Investigator

Assistant Professor, Department of Medicine, University of Minnesota Twin Cities

Division of Gastroenterology, Hepatology, and Nutrition

Faculty, Microbiology, Immunology and Cancer Biology (MICaB) PhD Graduate Program

Member, Masonic Cancer Center (MCC)

Member, Center for Genome Engineering (CGE)

Yundi Chen

Postdoc (2025- Present)

I'm a postdoc at the University of Minnesota Medical School. I’m interested in developing new CRISPR-based tools and applying them for genetic diseases.

Barbara Azevedo Machado

Graduate student (2025- Present)

I am a dentist and PhD student at the University of Minnesota. My research focuses on developing prime editing strategies for oral squamous cell carcinoma (OSCC). I aim to revert recurrent driver mutations and test therapeutic response in vitro, while also establishing local in vivo delivery of prime editing to the oral mucosa in a mouse model using lipid nanoparticles.

Roj Cosiquien

MD student (2024- Present)

I'm an MS1 at the University of Minnesota Medical School. I’m interested in the intersection of medicine, genetic technology, public health, and global health equity.

Anoop Dhamera

MD student (2025- Present)

I am an M1 at the University of Minnesota interested in Primary Care or an Internal Medicine subspecialty.

Pauline Cao

MD student (2025- Present)

I am an M1 at the University of Minnesota interested in Primary Care or an Internal Medicine subspecialty.

Jiaxin Wei

Researcher 1 (2025- Present)

My current research focused on HBV inactivation using prime editing. My broader interests include gene therapy, virology, and the translation of genetic technologies into therapeutic applications.

Isaiah Whalen

Researcher 1 (2024- Present)

Currently a junior studying Genetics and Biology and the University of Minnesota Twin Cities Campus.

Meet the team

Our team fosters a collaborative and innovative culture driven by curiosity, scientific rigor, and a shared commitment to advancing gene-editing technology. We value open communication, interdisciplinary teamwork, and a supportive environment where creative ideas and diverse perspectives drive impactful discoveries.

Join the team

We are looking for talented, creative, and ambitious individuals to join our team. with a strong background in genome editing, molecular biology, or immunotherapy.

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